[Postnatal development of rat progeny after antenatal nicotine exposure].

The authors studied the effect of a chemically pure nicotine on the development of the first-generation progeny after subcutaneous injection of the drug into female rats throughout the entire pregnancy. The drug was injected daily with a four-hour interval, the total doses being 5; 1,5 and 0.4 mg/kg (1/5, 1/20 and 1/70 of the LD50). Following nicotine… (More)