[Population pharmacokinetics of vancomycin from severe in patients with lower respiratory tract infection].

@article{Yang2017PopulationPO,
  title={[Population pharmacokinetics of vancomycin from severe in patients with lower respiratory tract infection].},
  author={Wen-ling Yang and Bei He and Cecilia H. Deng},
  journal={Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases},
  year={2017},
  volume={40 3},
  pages={205-209}
}
Objective: To develop a population pharmacokinetic (PPK) model of vancomycin in Chinese inpatients with severe lower respiratory tract infection. Methods: We gathered serum concentrations of vancomycin from inpatients who received vancomycin during Nov 2011 to Nov 2012.Vancomycin serum concentrations was measured by high performance liquid chromatography. Vancomycin PPK analysis was performed using nonlinear mixed effects model (NONMEM) program. Results: We gathered the data of 70 inpatients… CONTINUE READING