[Plasma insulin, IGF-I and breast cancer].

  • Rudolf Kaaks
  • Published 2001 in Gynecologie, obstetrique & fertilite


Several recent epidemiological studies have shown an increase in breast cancer risk among women who have elevated plasma levels of testosterone, reduced levels of sex hormone-binding globulin (SHBG), and hence elevated levels of bioavailable androgens and estrogens not bound to SHBG. This endocrine profile is generally associated with obesity and chronic… (More)