[Plasma concentrations of anionic uremic toxins in hemodialysis patients and their effects on protein binding of pravastatin].

Abstract

Uremic toxins (UTs) accumulate in the body of hemodialysis patients. UTs often exert unfavorable effects on patients and cause significant interactions with clinically relevant drugs. In this study, we assayed plasma concentrations of three typical anionic UTs, indoxyl sulfate (IS), 3-indoleacetic acid (IA), and 3-carboxy-4-methyl-5-propyl-2-furanpropionic… (More)
DOI: 10.1248/yakushi.14-00244

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