• Chemistry, Medicine
  • Published in Arzneimittel-Forschung 1975

[Pivampicillin and ampicillin in experimental E. coli pyelonephritis].

@article{Hubmann1975PivampicillinAA,
  title={[Pivampicillin and ampicillin in experimental E. coli pyelonephritis].},
  author={S Hubmann and Wilhelm Ritzerfeld},
  journal={Arzneimittel-Forschung},
  year={1975},
  volume={25 2},
  pages={
          168-9
        }
}
The antimicrobiol activity of 6-[D(--)-alpha-aminophenylacetamido]-penicillanic acid-(pivaloyloxymethyl)-ester (privampicillin) was tested in comparison to ampicillin during the acute ascending pyelonephritis of the rat caused by E. coli. Two groups of rats were treated with different drug concentrations; group I:3 times 70 mg/kg/day pivampicillin and 3 times 50 mg/kg/day ampicillin, group II: 3 times 70 mg/kg/day pivampicillin and 3 times 150 mg/kg/day ampicillin; controls were inoculated… CONTINUE READING

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