Corpus ID: 40690967

[Pineal hormone melatonin in low doses potentiates psychotropic and chronotropic activity of tofisopam in rats].

@article{Abrushanian2013PinealHM,
  title={[Pineal hormone melatonin in low doses potentiates psychotropic and chronotropic activity of tofisopam in rats].},
  author={{\'E}. B. Abrushanian and A. Popov},
  journal={Eksperimental'naia i klinicheskaia farmakologiia},
  year={2013},
  volume={76 4},
  pages={
          15-7
        }
}
Combination with a low dose of pineal hormone melatonin increased the anxiolytic effect of tofisopam (subthreshold dose) in open-field and cross-maze tests, as well as its chronotropic activity in time-course of forced swimming test in rats.