[Physiopathology of Rotavirus diarrhea].

  title={[Physiopathology of Rotavirus diarrhea].},
  author={Mathie M Lorrot and Monique Vasseur},
  journal={Archives de pediatrie : organe officiel de la Societe francaise de pediatrie},
  volume={14 Suppl 3},
The rotavirus is the major cause of infantile gastroenteritis. The virus infects the mature enterocytes of the villus tip of the small intestine and induces a watery diarrhea. Diarrhea can occur in the absence of histological changes in the intestine, and, conversely, the histological changes can be asymptomatic. Rotavirus decreases the activities of digestive enzymes at the apical brush border membrane and inhibits Na+ -solute cotransport systems. Accumulation of carbohydrates in the… CONTINUE READING
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