[Photodynamic therapy with verteporfin for uveal melanoma].

  title={[Photodynamic therapy with verteporfin for uveal melanoma].},
  author={Joachim Wachtlin and Nikolaos E. Bechrakis and Michael H. Foerster},
  journal={Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft},
  volume={102 3},
BACKGROUND The aim of this study was to evaluate whether photodynamic therapy (PDT) with verteporfin is able to induce tumor cell necrosis in human uveal melanomas. METHODS On four eyes with an uveal melanoma, PDT with verteporfin was performed on the tumor 2-3 days before planned enucleation. The eyes were evaluated histologically. RESULTS In two melanomas with only mild pigmentation some effects after PDT were detected on tumor tissue in a depth up to 2.5 mm at light doses > or =100 J/cm… CONTINUE READING


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