[Phosphorylation status of ASPP2 modulates p53 apoptotic function in oxaliplatin-induced apoptosis of colorectal cancer HCT116 cells].

@article{Hou2014PhosphorylationSO,
  title={[Phosphorylation status of ASPP2 modulates p53 apoptotic function in oxaliplatin-induced apoptosis of colorectal cancer HCT116 cells].},
  author={Qingsheng Hou and Hongwei Zhao and Weipeng Gong and Zhen-Yu Zhu and Yue Han and Dexi X Chen and Hongliang Guo},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={2014},
  volume={36 6},
  pages={418-23}
}
OBJECTIVE To investigate the role of apoptosis stimulating protein 2 of p53 (ASPP2) phosphorylation status in the regulation of ASPP2-p53 apoptotic pathway activity. METHODS Cells were individually transfected with green fluorescent protein (GFP)-encoding vector, constitutively non-phosphorylatable ASPP2 mutant-ASPP2 (Am)-encoding vector, and wild type… CONTINUE READING