Corpus ID: 13518468

[Pharmacology of prooxen].

@article{Vinogradov1980PharmacologyOP,
  title={[Pharmacology of prooxen].},
  author={Vladimir V. Vinogradov and Sergey S. Krylov},
  journal={Farmakologiia i toksikologiia},
  year={1980},
  volume={43 5},
  pages={
          563-6
        }
}
Prooxen--9-(3-dimethylaminopropyliden) xanthene--administered in small doses (0.05-0.1 mg/kg) produces a central and peripheral adrenosensibilizing effect, diminishes the duration of hexenal sleep, disturbs the differentiation, and causes appearance of intersignal reactions in experiments with conditioned reflexes. The drug exerts an antireserpine action. In large doses (5 mg/kg and over) it displays a tranquilizing action, prolongs the narcotic action of hexenal and chloral hydrate. LD50 and… Expand