Corpus ID: 21965504

[Pharmacological studies on oxatomide: (4) Effect on the histamine release from isolated rat peritoneal exudate cells (PEC) and lung slices].

@article{Ohmori1982PharmacologicalSO,
  title={[Pharmacological studies on oxatomide: (4) Effect on the histamine release from isolated rat peritoneal exudate cells (PEC) and lung slices].},
  author={K. Ohmori and H. Ishii and K. Shuto and N. Nakamizo},
  journal={Nihon yakurigaku zasshi. Folia pharmacologica Japonica},
  year={1982},
  volume={80 6},
  pages={
          441-9
        }
}

• K. Ohmori, H. Ishii, +1 author N. Nakamizo
• Published 1982
• Chemistry, Medicine
• Nihon yakurigaku zasshi. Folia pharmacologica Japonica

The present study was carried out to evaluate the inhibitory effect of oxatomide and disodium cromoglycate (DSCG) on the histamine release from rat PEC and lung slices induced by antigen-antibody reaction, concanavalin A, compound 48/80 and A-23187. Oxatomide in the range of 1 microM to 10 microM inhibited the allergic histamine release from rat PEC and lung slices induced by antigen-antibody reaction in the presence of phosphatidyl-L-serine (PS). Although the inhibitory action of oxatomide was… Expand

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