Corpus ID: 21965504

[Pharmacological studies on oxatomide: (4) Effect on the histamine release from isolated rat peritoneal exudate cells (PEC) and lung slices].

@article{Ohmori1982PharmacologicalSO,
  title={[Pharmacological studies on oxatomide: (4) Effect on the histamine release from isolated rat peritoneal exudate cells (PEC) and lung slices].},
  author={K. Ohmori and H. Ishii and K. Shuto and N. Nakamizo},
  journal={Nihon yakurigaku zasshi. Folia pharmacologica Japonica},
  year={1982},
  volume={80 6},
  pages={
          441-9
        }
}
The present study was carried out to evaluate the inhibitory effect of oxatomide and disodium cromoglycate (DSCG) on the histamine release from rat PEC and lung slices induced by antigen-antibody reaction, concanavalin A, compound 48/80 and A-23187. Oxatomide in the range of 1 microM to 10 microM inhibited the allergic histamine release from rat PEC and lung slices induced by antigen-antibody reaction in the presence of phosphatidyl-L-serine (PS). Although the inhibitory action of oxatomide was… Expand
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