[Pharmacologic effects of tofizopam (Grandaxin)].

  title={[Pharmacologic effects of tofizopam (Grandaxin)].},
  author={L Pet{\'o}cz},
  journal={Acta pharmaceutica Hungarica},
  volume={63 2},
  • L Petócz
  • Published 1993 in Acta pharmaceutica Hungarica
A great number of the anxiolytics used in the clinical practice are structurally 1,4-benzodiazepines. Tofisopam is the first derivative which differs from the so-called classical benzodiazepines in the position of the nitrogen atoms i.e. in the case of tofisopam they are vicinals (2.3-). This difference in its structure is suspected to be responsible for the different pharmacological and clinical profile of tofisopam. In addition to the anxiolytic activity, sedative, muscle relaxant and… CONTINUE READING