[Pharmacokinetics and therapeutic drug monitoring of anticancer agents].

  title={[Pharmacokinetics and therapeutic drug monitoring of anticancer agents].},
  author={Pierre Marquet and Annick Rousseau},
  journal={Bulletin du cancer},
  volume={95 10},
Treatment individualisation, an old concept renovated by the progress of analytical techniques and the advent of pharmacogenetics, aims at optimizing the usage of existing drugs by adjusting the nature and dose of anticancer agents to each patient, based on genetic, physiological and pathological criteria, on tumour nature, on associated drugs or previous treatment lines, on treatment efficacy and toxicity or on patient's exposure to the active drug form. This article exposes the pre-requisites… CONTINUE READING