[Pharmacokinetics, tolerance and therapeutic effect of trimethoprim-sulfametrol-infusions (author's transl)].

@article{Breyer1980PharmacokineticsTA,
  title={[Pharmacokinetics, tolerance and therapeutic effect of trimethoprim-sulfametrol-infusions (author's transl)].},
  author={Stephen G. Breyer and Winfried Graninger and Gerhart Hitzenberger},
  journal={Wiener medizinische Wochenschrift},
  year={1980},
  volume={130 12},
  pages={448-50}
}
Lidaprim was administered as infusion to 6 healthy volunteers for 10 days in an interval of 12 hours for calculation of the pharmacokinetic parameters. Furthermore 31 patients with various severe infectious diseases were treated for 5-27 days with 2 or 3 infusions daily. Local tolerance was excellent. Side effects were observed only in 1 patient, who… CONTINUE READING