Corpus ID: 24261986

[Pharmacokinetic study of pseudohainanensine with deuteriumlabeled analogue as internal standard].

@article{Gu1992PharmacokineticSO,
  title={[Pharmacokinetic study of pseudohainanensine with deuteriumlabeled analogue as internal standard].},
  author={Q. Gu},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={1992},
  volume={14 1},
  pages={
          51-3
        }
}
  • Q. Gu
  • Published 1992
  • Medicine
  • Zhonghua zhong liu za zhi [Chinese journal of oncology]
Pseudohainanensine (HH08) is a synthetic compound which is active against L-1210. In order to study the pharmacokinetic characteristics of this compound in rats, 3', 4'-dideuteropseudohainanensine (DH08) was synthesized and used as internal standard in GC-MS determination for quantitative analysis of alkaloid HH08 in the blood of rats that had been given HH08 at a dosage of 10 mg/kg intravenously. Experiments demonstrated that the detection limit of HH08 was 3 micrograms/ml and the peak… Expand