[Pharmacokinetic problems in clinical practice: role of drug transporters].

Abstract

Drug disposition is controlled by drug metabolism and drug transport. In the last decade numerous drug transporters have been identified and characterized in the context of drug uptake, efflux and interactions. This article reviews major advancements in this field. Efflux pumps like the multidrug resistance protein 1 (MDR1, ABCB1) are expressed in the… (More)
DOI: 10.1055/s-0028-1124005

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