[Pathological changes in the testes of the rats with hypospadia induced by dichlorvos].

@article{Huang2006PathologicalCI,
  title={[Pathological changes in the testes of the rats with hypospadia induced by dichlorvos].},
  author={Lu-gang Huang and Ping Lin and Chun-yu Gong and Jie Zhang and Qiao Hong Zhou and X Gong and Li Zeng},
  journal={Zhonghua nan ke xue = National journal of andrology},
  year={2006},
  volume={12 8},
  pages={693-5, 700}
}
OBJECTIVE To study the mechanism of dichlorvos leading to hypospadia of rats. METHODS From the 12th to the 17th day of conception, 20 pregnant female rats (the experiment group) were given 10 mg/(kg x d) dichlorvos, while another 10 (the control group) administered 1.5 ml 0.9% NaCl/day. Out of 88 male newborns of the 20 experimental mother rats, 22 had hypospadia, while out of the 33 male newborns of the 10 controls, none had the problem. Five hypospadia newborns from the experiment group and… CONTINUE READING

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