[Paris-I-Lariboisière variant thrombasthenia. Functional disorder of human platelet aggregation, glycoprotein-independent].

  • Jacques P. Caen
  • Published 1985 in
    Comptes rendus de l'Academie des sciences. Serie…


The present case of constitutional thrombasthenia is unique. It demonstrates the importance of the three major steps of human platelet aggregation: 1. binding of agonists to their respective membrane sites; 2. transmission of a message probably membrane Ca++ dependent, 3. exposure of the preformed GP IIb-III a complex allowing fibrinogen binding. We… (More)


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