[Painful generalized erythematous patches: A very rare cutaneous adverse effect of pemetrexed].

@article{CastellanosGonzlez2015PainfulGE,
  title={[Painful generalized erythematous patches: A very rare cutaneous adverse effect of pemetrexed].},
  author={Mar{\'i}a Castellanos-Gonz{\'a}lez and Javier Ballesteros Bargues},
  journal={Medicina clinica},
  year={2015},
  volume={145 8},
  pages={
          372-3
        }
}
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doi.org

References

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Painful generalized erythematous patches: a severe and unusual cutaneous reaction to pemetrexed.
Asteatotic eczema (‘eczema craquelé’) with histopathological interface dermatitis: a new cutaneous reaction following pemetrexed
TLDR
Three patients with widespread asteatotic eczema with a similar rash occurring 5–7 days after introduction of pemetrexed are described, with the clinical appearance of AE and the histopathological features of a drug reaction with interface dermatitis.
Pemetrexed-induced cellulitis: A rare toxicity in non-small cell lung cancer treatment
TLDR
A patient with advanced non-small-cell lung cancer who experienced bilateral peripheral edema after pemetrexed administration is reported, which is generally a well-tolerated drug.
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TLDR
The appearance of skin lesions is an indication for careful follow-up for evidence of Lyell's syndrome for which intensive management is needed.
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This review will focus on the cutaneous side effects of the newer classes of chemotherapy drugs, including targeted monoclonal antibody therapy and small molecule inhibitors.