[PPARgamma agonists for the diseases of gastrointestinal tract and liver].

Peroxisome proliferator-activated receptor gamma (PPARgamma), a member of the nuclear receptor superfamily, is expressed in colonic epithelial cells at high levels and is assumed to play an important physiological role in the gut. In vitro as well as animal model experiments showed considerable anti-cancer and anti-inflammatory effects of thiazolidinedione… CONTINUE READING