Corpus ID: 8470906

[Oxatomide and calcium: mechanisms involved in the secretion of mast cell mediators].

@article{Bueb1990OxatomideAC,
  title={[Oxatomide and calcium: mechanisms involved in the secretion of mast cell mediators].},
  author={J. Bueb and Y. Landry},
  journal={Annales de dermatologie et de venereologie},
  year={1990},
  volume={117 Suppl 1},
  pages={
          5-9
        }
}
  • J. Bueb, Y. Landry
  • Published 1990
  • Biology, Medicine
  • Annales de dermatologie et de venereologie
Human cutaneous mast cells and their experimental model rat peritoneal mast cells, can be stimulated by an IgE-dependent process or by peptides through the direct activation of G proteins. Both activation pathways lead to the increase of cytosolic Ca2+ level. This increase in dependent of the mobilisation of intracellular calcium stores of the endoplasmic reticulum involving the stimulation of IP3-sensitive calcium channels. Mast cells are characterized by the absence of calcium channels in the… Expand
1 Citations