[Ovalbumin sensitization affects nonadrenergic noncholinergic relaxation response on guinea-pig tracheal smooth muscle].

@article{Takatsuki2000OvalbuminSA,
  title={[Ovalbumin sensitization affects nonadrenergic noncholinergic relaxation response on guinea-pig tracheal smooth muscle].},
  author={Kiyoshi Takatsuki and Yoshihiro Nishimura and Hiroyuki Maeda and Mitsuhim Yokoyama},
  journal={Arerugi = [Allergy]},
  year={2000},
  volume={49 7},
  pages={562-8}
}
We investigated the effects of anaphylactic challenge on nonadrenergic noncholinergic (NANC) relaxation response to electrical field stimulation (EFS) or to aminophylline in sensitized guinea pig tracheal smooth muscles. An anaphylactic challenge with ovalbumin (OA) reduced the relaxation response to EFS (20 V. 5 Hz. 300 pulse. duration 1 msec.), but the relaxation response to aminophylline was not affected by OA exposure. NG-monomethyl L-arginine, a nitric oxide (NO) synthesis inhibitor… CONTINUE READING