[Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study].

@article{Bakan2015OpioidfreeTI,
  title={[Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study].},
  author={Mefkur Bakan and Tarik Umutoglu and Ufuk Topuz and Harun Uysal and M. Can Bayram and H{\"u}seyin Kadioǧlu and Ziya Salihoğlu},
  journal={Revista brasileira de anestesiologia},
  year={2015},
  volume={65 3},
  pages={191-9}
}
BACKGROUND AND OBJECTIVES Intraoperative use of opioids may be associated with postoperative hyperalgesia and increased analgesic consumption. Side effects due to perioperative use of opioids, such as postoperative nausea and vomiting may delay discharge. We hypothesized that total intravenous anesthesia consisting of lidocaine and dexmedetomidine as an opioid substitute may be an alternative technique for laparoscopic cholecystectomy and would be associated with lower fentanyl requirements in… CONTINUE READING