[Ondansetron as prophylaxis for postoperative nausea and vomiting. A prospective randomized double-blind comparative study with droperidol].

@article{Alon1994OndansetronAP,
  title={[Ondansetron as prophylaxis for postoperative nausea and vomiting. A prospective randomized double-blind comparative study with droperidol].},
  author={Eli Alon and Peter Biro and Philipp M. Lenzlinger and Peter G. Atanassoff},
  journal={Der Anaesthesist},
  year={1994},
  volume={43 8},
  pages={500-3}
}
Ondansetron, a selective 5-HT3 receptor antagonist, has recently been shown, in a dose of 8 mg, to be superior to 1.25 mg droperidol in preventing postoperative vomiting. There are indications that a dose of 4 mg of ondansetron may be just as effective in reducing postoperative nausea and vomiting as a dose of 8 mg. The aim of this study was to evaluate the efficacy and the adverse effects of 4 mg ondansetron in the prevention of postoperative nausea and vomiting compared to droperidol in… CONTINUE READING

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AlfentanilMay preventPain
On pain stimuli another 0.2 - 0.4 mg of alfentanil was given .
Sixteen patients in the droperidol group and 8 patients in the ondansetron group showed a total effective antiemetic response ( P < 0.05 ) .
Sixteen patients in the droperidol group and 8 patients in the ondansetron group showed a total effective antiemetic response ( P < 0.05 ) .
Sixteen patients in the droperidol group and 8 patients in the ondansetron group showed a total effective antiemetic response ( P < 0.05 ) .
The drugs were given intravenously prior to general anaesthesia for minor gynaecological surgery with nitrous oxide and enflurane in oxygen supplemented with small boluses of alfentanil .
Anaesthesia was induced with 2.1 - 4 mg / kg of thiopental and 0.1 mg of alfentanil i.v . and maintained with 65% nitrous oxide and 1.5%-3% enflurane in oxygen .
The drugs were given intravenously prior to general anaesthesia for minor gynaecological surgery with nitrous oxide and enflurane in oxygen supplemented with small boluses of alfentanil .
Anaesthesia was induced with 2.1 - 4 mg / kg of thiopental and 0.1 mg of alfentanil i.v . and maintained with 65% nitrous oxide and 1.5%-3% enflurane in oxygen .
Anaesthesia was induced with 2.1 - 4 mg / kg of thiopental and 0.1 mg of alfentanil i.v . and maintained with 65% nitrous oxide and 1.5%-3% enflurane in oxygen .
Anaesthesia was induced with 2.1 - 4 mg / kg of thiopental and 0.1 mg of alfentanil i.v . and maintained with 65% nitrous oxide and 1.5%-3% enflurane in oxygen .
Anaesthesia was induced with 2.1 - 4 mg / kg of thiopental and 0.1 mg of alfentanil i.v . and maintained with 65% nitrous oxide and 1.5%-3% enflurane in oxygen .
Anaesthesia was induced with 2.1 - 4 mg / kg of thiopental and 0.1 mg of alfentanil i.v . and maintained with 65% nitrous oxide and 1.5%-3% enflurane in oxygen .
Sixteen patients in the droperidol group and 8 patients in the ondansetron group showed a total effective antiemetic response ( P < 0.05 ) .
Sixteen patients in the droperidol group and 8 patients in the ondansetron group showed a total effective antiemetic response ( P < 0.05 ) .
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