[On the inhibition of thrombocyte aggregation by bupranolol / Aggregometric and electron microscopic study in vitro (author's transl)].

@article{Zwillenberg1980OnTI,
  title={[On the inhibition of thrombocyte aggregation by bupranolol / Aggregometric and electron microscopic study in vitro (author's transl)].},
  author={L. O. Zwillenberg and G B{\"o}siger},
  journal={Arzneimittel-Forschung},
  year={1980},
  volume={30 3},
  pages={483-7}
}
The ADP-induced primary aggregation of human thrombocytes in vitro was inhibited by 1.5X10(-4) mol/l (+/-)bupranolol. At this concentration a strong desaggregation was obtained. The stereoisomers of bupranolol did not differ in effectiveness. Fractional addition was just as effective as a single dose. Not beta-receptor blocking but a membrane stabilizing… CONTINUE READING