• Corpus ID: 12907301

[Nutrition, acid-base metabolism, cation-anion difference and total base balance in humans].

@article{Mioni2008NutritionAM,
  title={[Nutrition, acid-base metabolism, cation-anion difference and total base balance in humans].},
  author={R. Mioni and P. Sala and Giuseppe Mioni},
  journal={Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia},
  year={2008},
  volume={25 4},
  pages={
          407-21
        }
}
  • R. Mioni, P. Sala, G. Mioni
  • Published 1 July 2008
  • Chemistry, Biology
  • Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia
The relationship between dietary intake and acid-base metabolism has been investigated in the past by means of the inorganic cation-anion difference (C(+)(nm)-A(-)(nm)) method based on dietary ash-acidity titration after the oxidative combustion of food samples. Besides the inorganic components of TA (A(-)(nm)-C(+)(nm)), which are under renal control, there are also metabolizable components (A(-)(nm)-C(+)(nm)) of TA, which are under the control of the intermediate metabolism. The whole body… 
Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality
TLDR
A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health.