[Noninvasive detection of experimental vulnerable atherosclerotic plaques with 99Tc m labeled C2A domain of synaptotagmin I].

Abstract

OBJECTIVE (99)Tc(m) labeled C2A domain of synaptotagmin I ((99)Tc(m)-Syt I-C2A) is used for noninvasive detection of vulnerable atherosclerotic plaque. METHODS Recombinant C2A domain of synaptotagmin I, overexpressed in E. Coli, was thiolated with 2-iminothiolane (2-IT) and labeled with (99)Tc(m). Atherosclerotic plaques were produced in 5 rabbits by… (More)

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@article{Fang2007NoninvasiveDO, title={[Noninvasive detection of experimental vulnerable atherosclerotic plaques with 99Tc m labeled C2A domain of synaptotagmin I].}, author={Wei Fang and Shun-dong Ji and Feng Wang and Min-Fu Yang and Bin L{\"u} and Lei Liu and Zi-zheng Wang and Zuo-xiang He}, journal={Zhonghua xin xue guan bing za zhi}, year={2007}, volume={35 2}, pages={178-81} }