[Non-enzymatic glycosylation of lipoproteins in the pathogenesis of atherosclerosis in diabetics].


A significant factor associated with hiperglycaemia in diabetes is the resultant post-translational non-enzymatic glycation of plasma and cellular proteins. This process occurs in vivo by direct chemical reaction of glucose with protein alpha and epsilon amino groups. Because of the diverse evidences for direct involvement of non-enzymatic glycation of… (More)


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