• Corpus ID: 7205912

[Nocturnal hypertension and sleep apnea: effect of the ACE inhibitor cilazapril on apnea-induced blood pressure increases during sleep].

@article{Grote1995NocturnalHA,
  title={[Nocturnal hypertension and sleep apnea: effect of the ACE inhibitor cilazapril on apnea-induced blood pressure increases during sleep].},
  author={Ludger Grote and A Radeck and J{\"o}rg Heitmann and W Althaus and Thomas Ploch and J{\"o}rg Hermann Peter and Peter von Wichert},
  journal={Pneumologie},
  year={1995},
  volume={49 Suppl 1},
  pages={
          170-4
        }
}
The nocturnal increases in blood pressure in cases of obstructive sleep apnea are discussed as causes in connection with increased cardiovascular mortality in sleep apnea. Previous antihypertension therapy studies revealed the antihypertensive action of the ACE inhibitor cilazapril averaged over NREM (NR) and REM sleep (R). In the present study, the effect of this drug on the blood pressure increase within the stress segment of obstructive apnea in NR and R was investigated in a double-blind… 
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