[Nifedipine in the treatment of chronic cor pulmonale].

  title={[Nifedipine in the treatment of chronic cor pulmonale].},
  author={Alain Y Saadjian and François Philip-Joet and A Tran N'guyen and Antoine Arnaud and Janine Torr{\'e}sani},
  journal={Archives des maladies du coeur et des vaisseaux},
  volume={79 1},
The effects of a single dose of nifedipine (20 mg sublingual) on the haemodynamics and parameters of tissue oxygenation were assessed by right heart catheterisation and oximetry of mixed arterial and venous blood in 24 patients with pulmonary hypertension secondary to severe chronic obstructive airways disease. The haemodynamic effects of 15 days' oral therapy (30 mg/day) were studied in 10 other patients. Significant improvement in right ventricular pump function (25 p. 100 increase in cardiac… CONTINUE READING