[Neuroprotector effect of human recombinant erythropoietin sorbed on polymer nanoparticles studied on model of intracerebral post-traumatic hematoma (hemorrhagic stroke)].

@article{Balabanian2011NeuroprotectorEO,
  title={[Neuroprotector effect of human recombinant erythropoietin sorbed on polymer nanoparticles studied on model of intracerebral post-traumatic hematoma (hemorrhagic stroke)].},
  author={V Iu Balaban'ian and I. N. Solev and O. S. Elizarova and Taissia L Garibova and S. A. Litvinova and Tatiana A Voronina},
  journal={Eksperimental'naia i klinicheskaia farmakologiia},
  year={2011},
  volume={74 10},
  pages={
          17-22
        }
}
The neuroprotective activity of recombinant human erythropoietin (r-HuEpo) sorbed on poly(butyl)cyanoacrilate nanoparticles (EPO-PBCA) and on polylactic-co-glycolic acid nanoparticles (EPO-PLGA) has been studied on Wistar rats with intracerebral post-traumatic hematoma (model of hemorrhagic stroke) (IPH-HS) in comparison to native r-HuEpo. It is established that EPO-PBCA produced a protective effect in rats after IPH-HS that was manifested by a decrease in the number of animals with… CONTINUE READING