[Neuropeptide-mediated transmission of nociceptive information and its regulation. Novel mechanisms of analgesics].

  • Yasushi Kuraishi
  • Published 1990 in
    Yakugaku zasshi : Journal of the Pharmaceutical…


Substance P and somatostatin may be transmitters of nociceptive information, which are involved in the transmission of pressure and heat nociceptive information, respectively, in the spinal dorsal horn. Calcitonin gene-related peptide, which is present in the primary sensory neurons having substance P or somatostatin, may function as a pain-promoting… (More)


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