[Neuroinflammation in amyotrophic lateral sclerosis].

  title={[Neuroinflammation in amyotrophic lateral sclerosis].},
  author={Fumito Endo and Koji Yamanaka},
  journal={Rinsho shinkeigaku = Clinical neurology},
  volume={54 12},
Neuroinflammation, characterized by activated astrocytes and microglia, infiltrated T cells, and the subsequent production of inflammatory mediators, is a pathological hallmark of amyotrophic lateral sclerosis (ALS). Since microglia produce proinflammatory cytokines and other neurotoxic or protective molecules and astrocytes reduce their glutamate uptake… CONTINUE READING