[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].

@article{Gao2012MutationsOK,
  title={[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].},
  author={Jing Gao and Zhi-Wei Sun and Yan-Yan Li and Lin Shen},
  journal={Zhonghua bing li xue za zhi = Chinese journal of pathology},
  year={2012},
  volume={41 9},
  pages={579-83}
}
OBJECTIVE To identify the mutation rate of KRAS and BRAF in Chinese patients with colorectal carcinoma (CRC), and to analyze the associations between KRAS/BRAF mutations and patients' clinicopathological characteristics. METHODS Tumor specimens were obtained from 966 CRC patients treated in Peking University Cancer Hospital from December 2008 to January 2012. Mutation analysis of KRAS (codons 12 and 13 of exon 2) and BRAF (exon 15) was conducted by direct sequencing. The relationships between… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
5 Extracted Citations
0 Extracted References
Similar Papers