[Mutation-specific antibodies for detection of epidermal growth factor receptor mutations in patients with lung adenocarcinoma].

Abstract

OBJECTIVE To examine the sensitivity and specificity of the two epidermal growth factor receptor hotspot mutation antibodies-delE746-A750 and L858R in lung adenocarcinoma, and to discuss the value of the two antibodies for detecting these two "classic mutations" by immunohistochemistry. METHODS With Q-scoring assessment and ROC curve analysis… (More)
DOI: 10.3760/cma.j.issn.0529-5807.2013.03.006

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