[Morphological changes in the intestinal mucosa of the large intestine under the blockage of H+,K+ -ATPase and CCK-2 gastrin receptors].

Abstract

In experiments on rats, a 14-days blockade of H-,K- -ATPase with lansoprazole was revealed to cause structural disorders in the epitheliocytes and goblet cells, enhancement of proliferation processes in the mucous membrane of large intestine and increase of gastrin concentration in blood. The blockade of H-,K+ -ATPase in epitheliocytes elicited an… (More)

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