• Corpus ID: 222237071

[Monoclonal integration of simian T-cell leukemia virus in hamadryas with malignant lymphoma].

@article{Ag1990MonoclonalIO,
  title={[Monoclonal integration of simian T-cell leukemia virus in hamadryas with malignant lymphoma].},
  author={D'iachenko Ag and Kondzhariia Ig and I. Ev and Lapin Ba and Iakovleva La and Rudaia Ld and Dzhalagoniia Bl},
  journal={Eksperimentalʹnai︠a︡ onkologii︠a︡},
  year={1990},
  volume={12},
  pages={15}
}
The association of simian T-cell leukemia virus with baboons malignant lymphoma was studied. Proviral DNA integrated in cells of lymphoid organs was detected in 19 of 21 sick animals examined. Only 4 of 10 monkeys from high risk colony without clinical manifestations had virus-specific sequences in their cellular DNAs. As a rule, S(H)TLV-I-infected cells monoclonally proliferated both in lymphomatous and healthy baboons. The restriction patterns with EcoRI, HindIII, PstI, BamHI of S(H)TLV-I… 
2 Citations

Interspecies transmission of macaque simian T-cell leukemia/lymphoma virus type 1 in baboons resulted in an outbreak of malignant lymphoma

TLDR
Interspecies transmission of STLV-1 from rhesus macaques (or closely related species) to baboons occurred at Sukhumi Primate Center and most probably this event initiated the outbreak of lymphoma inSukhumi baboons.

Neoplasia/Proliferative Disorders