[Modulation of matrix metalloproteinase by dexamethasone in airway remodeling in asthmatic rats].

@article{Yuan2003ModulationOM,
  title={[Modulation of matrix metalloproteinase by dexamethasone in airway remodeling in asthmatic rats].},
  author={Yiming Yuan and Zengli Wang and Birong Dong},
  journal={Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition},
  year={2003},
  volume={34 4},
  pages={680-3}
}
OBJECTIVE To observe the effect of dexamethasone on airway remodeling and to explore the significance of the balance between matrix metalloproteinase and the tissue inhibitor of metalloproteinase. METHODS Thirty male Wistar rats were randomly divided into asthmatic group (n = 10), dexamethasone group (n = 10) and control group (n = 10). Lung tissues were sliced and stained with H. E. The parameters such as bronchial basement membrane perimeter(Pbm), total bronchial wall area(WAt), inner wall… CONTINUE READING
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