Corpus ID: 34883385

[Mifepristone inhibits the progesterone-induced expressions of HLA-G, -E, -F genes in trophoblasts during first trimester].

@article{Zeng2012MifepristoneIT,
  title={[Mifepristone inhibits the progesterone-induced expressions of HLA-G, -E, -F genes in trophoblasts during first trimester].},
  author={Bin Zeng and Y. Wang and Yang Zhang and A. Liao},
  journal={Zhonghua yi xue za zhi},
  year={2012},
  volume={92 1},
  pages={
          15-7
        }
}
  • Bin Zeng, Y. Wang, +1 author A. Liao
  • Published 2012
  • Medicine
  • Zhonghua yi xue za zhi
  • OBJECTIVE To explore the effects of mifepristone on the expressions of HLA-G, HLA-E and HLA-F in extravillous cytotrophoblasts (EVCT). METHODS Cultured EVCT during the first trimester were treated in vitro with progesterone and mifepristone. And the transcription levels of HLA-G, HLA-E and HLA-F genes were detected by RT-PCR (reverse transcription-polymerase chain reaction). RESULTS As compared with the controls, the levels of HLA-G, HLA-E and HLA-F mRNA significantly increased in EVCT… CONTINUE READING