[Microsatellite instability of sporadic colorectal carcinomas and its clinicopathological significance].

@article{Xiao2006MicrosatelliteIO,
  title={[Microsatellite instability of sporadic colorectal carcinomas and its clinicopathological significance].},
  author={Xiu-Ying Xiao and Xiaoyan Zhou and Meng-hong Sun and Ge Yan and Xiang Du},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={2006},
  volume={28 4},
  pages={289-93}
}
OBJECTIVE To investigate the incidence of microsatellite instability (MSI) in sporadic colorectal carcinoma (CRC) using BAT-25 and BAT-26 loci, and its association with clinicopathological features. METHODS Microsatellite analysis was performed on tissue samples from 73 primary and 53 metastatic tumors collected at the Department of Pathology, Fudan University Cancer Hospital in 2002. Genomic DNA was extracted from paraffin-embedded tissues. Microsatellite alterations of BAT-25 and BAT-26… CONTINUE READING