[Microsatellite instability among patients with colorectal cancer].

@article{Montenegro2006MicrosatelliteIA,
  title={[Microsatellite instability among patients with colorectal cancer].},
  author={Yenny M. Montenegro and Jos{\'e} Luis Ram{\'i}rez-Castro and Luis Fernando L{\'o}pez Isaza and Gabriel Bedoya and Carlos Mario Mu{\~n}et{\'o}n-Pe{\~n}a},
  journal={Revista medica de Chile},
  year={2006},
  volume={134 10},
  pages={
          1221-9
        }
}
BACKGROUND In patients with colorectal carcinoma, insertions or deletions of short sequences of DNA, a phenomenon called microsatellite instability, are observed. AIM To look for microsatellite instability and mutations of MLH1 and MSH2 gene mutations in patients with colorectal carcinoma. MATERIAL AND METHODS Ten patients with sporadic colorectal carcinoma and 31 patients fulfilling criteria for hereditary nonpolyposis colon cancer (HNPCC), aged 9 to 70 years, were studied. Microsatellite… CONTINUE READING

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