[MicroRNA-10a accelerates endodermal lineage differentiation of mesenchymal stem cells from human placenta].

Abstract

OBJECTIVE To improve the potential of endodermal differentiation of human placenta-derived mesenchymal stem cells (PMSCs) by microRNA-10a (miR-10a)-mediated post-transcriptional regulation of its mRNA targets. METHODS Lentiviral vectors were used to stably and specifically over-express miR-10a and inhibited the miR-10a function by its antagomir. In… (More)

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