Corpus ID: 22430294

[Methylation status of JunB and CDH13 gene promoter in CD34(+)CD38(-) chronic myelogenous leukemia cells].

@article{Wang2009MethylationSO,
  title={[Methylation status of JunB and CDH13 gene promoter in CD34(+)CD38(-) chronic myelogenous leukemia cells].},
  author={Xiao-juan Wang and Juan Li and Bing-Jie Fu and Linlin Guo and Jia-hua Zhang and Shi-ang Huang},
  journal={Zhongguo shi yan xue ye xue za zhi},
  year={2009},
  volume={17 6},
  pages={
          1405-8
        }
}
Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disease of transformed hematopoietic progenitor cells. The expressions of JunB and CDH13 (cadherin-13) gene as tumor suppressor gene were inactivated by promoter methylation in CML patients. This study was purposed to investigate the methylation difference of JunB and CDH13 gene promoter and the expression levels of JunB and CDH13 gene in CD34(+)CD38(-) cells in CML patients vs normal individuals. CD34(+)CD38(-) cells from 8… Expand
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