[Methotrexate and psoriasis].

  title={[Methotrexate and psoriasis].},
  author={Irina Bournerias},
  journal={La Revue du praticien},
  volume={41 22},
Methotrexate is effective in the treatment of severe psoriasis. If recommended guidelines are strictly followed the drug, administered in low doses, is not dangerous. The main adverse effect is cumulative hepatotoxicity. Hematologic toxicity occurs especially if other medications are associated.