[Methods for the appraisal of the safety of antiseptics (author's transl)].


A procedure is described, topical applications for testing dermal toxicity of antiseptics. The tests for irritancy are made on Guinea pigs: a closed patch test giving us a primary irritation index, and prolonged applications over periods of 90 days giving a superficial aggressivity index. The standard method of testing animals for irritation of the skin is… (More)