Corpus ID: 556481

[Methanol, isopropanol, n-propanol--endogenous formation affected by alcohol?].

  title={[Methanol, isopropanol, n-propanol--endogenous formation affected by alcohol?].},
  author={R. Iffland and P. Balling and M. Oehmichen and F. Lieder and T. Norpoth},
  volume={26 2},
Methanol, isopropanol and n-propanol are detected usually in blood samples during the determination of congeners. The ethanol-induces formation of methanol and isopropanol has been described formerly. Also little amount of n-propanol were detected in blood, which could not be reduced to the alcoholic beverages. 
15 Citations
Alcohol Congeners and the Source of Ethanol
Alcoholic beverages contain, besides ethanol, a number of volatile compounds that contribute to their taste and odor. Gas chromatography with headspace analyses can be used to identify and quantifyExpand
Methanol and congeners as markers of alcohol use and abuse
Congener analysis and especially methanol contribute to evaluate and differentiate a declared consumption of various alcoholic beverages, e.g. to judge post offence drinking claims. Methanol withExpand
Concentration of ethanol and other volatile compounds in the blood of acutely poisoned alcoholics.
The presence of volatile compounds, such as acetone, acetaldehyde, methanol, ethanol, isopropanol, and n-propanol, in the blood of 169 acutely poisoned alcoholics was determined and seems to indicate that, in heavy drinkers, the elimination of meethanol may be relatively fast even if the ethanol concentration is above 1 g/l. Expand
Alcohol congener analysis and the source of alcohol: a review
This novel approach may reduce current limitations that exist with traditional methods of detecting fermentation by-product congeners, which restrict the use of alcohol congener analysis internationally and for other medico-legal scenarios. Expand
Optimization of solid-phase microextraction conditions for gas chromatographic determination of ethanol and other volatile compounds in blood.
For each analyte, the limits of detection and quantification, linearity, working range, accuracy and precision were determined or tested and the worked-out method was performed. Expand
Endogenous methanol: variability in concentration and rate of production. Evidence of a deep compartment?
It is hypothesised that there may be a so-called deep compartment for methanol that would explain the dependence of the endogenous meethanol level on the duration of the preceding period of abstinence from ethanol, and the occurrence of an initial phase of faster rise in metanol concentration associated with the administration of ethanol. Expand
Evaluation and review of ways to differentiate sources of ethanol in postmortem blood
Various ways to establish the source of ethanol in PM blood are reviewed, including collection and analysis of alternative specimens, the identification of non-oxidative metabolites of ethanol, ethyl glucuronide and ethyl sulfate, the urinary metabolites of serotonin, and identification of n-propanol and n-butanol in blood, which are known putrefaction products. Expand
Changes in the concentrations of ethanol, methanol and metabolites of serotonin in two successive urinary voids from drinking drivers.
Finding raised concentrations of methanol and a high 5HTOL/5HIAA ratio in urine specimens provides additional evidence to confirm recent drinking. Expand
The elimination kinetics of methanol and the influence of ethanol
The elimination of methanol administered alone was found to follow first-order kinetics with a rate constant for the elimination phase of 0.475-0.259 h−1, corresponding to an elimination half-life of 1.8-3.0h. Expand
Dermal and pulmonary absorption of propan-1-ol and propan-2-ol from hand rubs.
Based on the experimental data, the risk of chronic systemic toxic effects caused by hand rubs is likely negligible and the consequences of long-term daily and frequent use of hygienic hand Rubs are likely negligible. Expand