[Metformin efficacious in poorly controlled diabetes mellitus type 2].

@article{Stades2000MetforminEI,
  title={[Metformin efficacious in poorly controlled diabetes mellitus type 2].},
  author={Aline M E Stades and Frits Holleman and Joost B. L. Hoekstra},
  journal={Nederlands tijdschrift voor geneeskunde},
  year={2000},
  volume={144 40},
  pages={1897-900}
}
Three patients, 1 man and 2 women, aged 60, 55 and 72 years, had an insufficient glucose regulation with insulin therapy or with sulfonylurea derivatives. They started metformin therapy, after which HbA1c decreased by 0.8-1.8%. One patient had to discontinue metformin therapy due to excessive diarrhoea. Many studies have shown the beneficial effect of… CONTINUE READING