[Metabolism and pharmacokinetics of acemetacin in man (author's transl)].

  title={[Metabolism and pharmacokinetics of acemetacin in man (author's transl)].},
  author={H D Dell and M Doersing and Werner Fischer and H P Jacobi and Roza Maria Kamp and G. W. K{\"o}hler and G{\"u}nter Sch{\"o}llnhammer},
  volume={30 8A},
Metabolism and pharmacokinetics of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetoxy]-acetic acid (acemetacin, TV 1322, Rantudil) in comparison to equimolar doses of indometacin was investigated in human volunteers after a single oral application and in rheumatic patients after multiple application. After multiple application (t.i.d. for 10 days) of equimolar doses of acemetacin and indometacin, mean blood level curves. The bioavailability of acemetacin derived from these data… CONTINUE READING