[Metabolic activation of chondrocytes in human osteoarthritis. Expression of type II collagen].

@article{Pullig1999MetabolicAO,
  title={[Metabolic activation of chondrocytes in human osteoarthritis. Expression of type II collagen].},
  author={Oliver Pullig and Beth Kladny and Gerd Weseloh and Bernd Swoboda},
  journal={Zeitschrift fur Orthopadie und ihre Grenzgebiete},
  year={1999},
  volume={137 1},
  pages={67-75}
}
OBJECTIVE/METHODS Type II collagen is the dominating collagen in articular cartilage. It is essential for the structural integrity and the biomechanical properties of cartilage. Using immunohistology and in situ hybridization we systematically analyzed the protein and mRNA-expression of type II collagen in cartilage/bone sections without any signs of osteoarthritis and osteoarthritic samples with various degrees of osteoarthritis. RESULTS In normal articular cartilage without any histologic… CONTINUE READING