[Mechanism of the mitogen-activated protein kinase phosphatase-5 regulating the growth and invasion of a human prostate cancer cell line].

@article{He2003MechanismOT,
  title={[Mechanism of the mitogen-activated protein kinase phosphatase-5 regulating the growth and invasion of a human prostate cancer cell line].},
  author={Hui-ying He and Wei-gang Fang and Jie Zheng and Jiang-feng You and Wan-jie Heng and Yan Li},
  journal={Zhonghua yi xue za zhi},
  year={2003},
  volume={83 20},
  pages={1812-7}
}
OBJECTIVE To investigate the effects of mitogen-activated protein kinase phosphatase-5 (MKP5) on the biological behaviors of cell and the activation of mitogen-activated protein kinase (MAPK) induced by P2Y purinergic receptor agonist ATP in the prostate cancer cell line 1E8. METHODS 1E8 cells were cultured. The recombinant plasmid pcDL-SRalpha296-MKP5 containing the human wild type MKP5 cDNA and blank vector pcDL-SRalpha were co-transfected with pcDNA3 vector plasmid into the 1E8 cells… CONTINUE READING